Latest publication : fluorescence cross-correlation spectroscopy in a nanoaperture

4 Janvier 2007 , Rédigé par JW Publié dans #Recent research work

Our latest publication has now been released :

J. Wenger, D. Gérard, P. -F. Lenne, H. Rigneault, J. Dintinger, T. W. Ebbesen, A. Boned, F. Conchonaud, and D. Marguet, " Dual-color fluorescence cross-correlation spectroscopy in a single nanoaperture : towards rapid multicomponent screening at high concentrations," Opt. Express 14, 12206-12216 (2006)

It describes the first experimental implementation of nanometric apertures to conduct dual-color fluorescence cross-correlation spectroscopy (FCCS) at high molecular concentrations.

Nanoapertures have already been demonstrated to be useful for single-color FCS analysis [see Levene et al, Science 299, 682-686 (2003)]. Surprisingly, the extension to the dual-color case has never been reported and yet new interesting specificities are described and detailed in this article (simple microscope setup, no confocal pinhole, micromolar concentrations).

As we paid a substantial fee of $1200, this paper is freely available to ALL readers at :
http://www.opticsexpress.org/abstract.cfm?id=119765