Latest (review) paper : nanophotonics and FCS

10 Février 2010 , Rédigé par JW Publié dans #Recent research work

Published in the January issue of Int. J. Mol. Sci., this review is freely available for download here (4.1Mb).

Abstract: Recent advances in nanophotonics open the way for promising applications towards efficient single molecule fluorescence analysis. In this review, we discuss how photonic methods bring innovative solutions for two essential questions: how to detect a single molecule in a highly concentrated solution, and how to enhance the faint optical signal emitted per molecule? The focus is set primarily on the widely used technique of fluorescence correlation spectroscopy (FCS), yet the discussion can be extended to other single molecule detection methods.