World's smallest FCS apparatus

25 Mai 2010 , Rédigé par JW Publié dans #Recent research work

My group has recently developed an integrated system for compact and portative single molecule fluorescence analysis without using any microscope or microscope objective.

 

The system is based on our patented technology based on a glass microsphere at the end of the optical fiber. The microsphere works as a tiny lens to focus light with focusing capabilities close to that of a high-quality microscope objective.

 

The system is capable of single molecule fluorescence correlation spectroscopy (FCS) and fluorescence lifetime histograming (TCSPC). The size is roughly that of an A3 format, that makes it the world’s smallest FCS system to date, and much more integration is readily feasible.

 

See a complete article here.

 

http://www.fresnel.fr/spip/spip.php?action=acceder_document&arg=831&cle=5f933f42eebb2ba64f7fefff889e64b2&file=jpg%2FIMG_2676.jpg