Latest paper : nanoaperture enhanced fluorescence for fast FCS analysis
Published in January 15th issue of Analytical Chemistry :
http://pubs.acs.org/doi/abs/10.1021/ac8024015
The manuscript presents a thorough study of the signal-to-noise improvement in Fluorescence Correlation Spectroscopy (FCS) measurements within a nanoaperture. We believe that this will enable a large variety of new applications of FCS. The paper demonstrates a 10x quality improvement of FCS measurements when using nanoapertures. The graph below shows the quality enhancement of correlation curves for fluorescence molecules in open solution or inside a gold nanoaperture :