Jerome Wenger NanoBioPhotonics

SPIE Photonics West Proceedings 1

2 Avril 2010 , Rédigé par JW Publié dans #Recent research work

Following in SPIE Photonics West conference in last January, we have a proceedings paper published.

High-efficiency single molecule fluorescence detection and correlation spectroscopy with dielectric microspheres
H. Aouani, N. Djaker, J. Wenger, and H. Rigneault, Proc. of SPIE, Proc. SPIE Vol. 7571, pp.75710A (2010)

A personal reprint can be found here.

We report of the following new results :

- microspheres made of high refractive index melamine resin provide a seven-fold fluorescence enhancement on single molecules.

- this effect can be used to increase the signal-to-noise ratio in fluorescence correlation spectroscopy and reduce the experiment integration time by fifty-fold.

- first description of dual-color fluorescence cross-correlation spectroscopy (FCCS) enhanced by a microsphere.

My first article in Micscape

28 Mars 2010 , Rédigé par JW Publié dans #Fancy lab

For those of you who do academic research on (nano)photonics but don't know about the Micscape journal, then you're definitely missing one of the major publications about microscopy

It's loaded with plenty of useful / interesting / futile* stuff (* choose the word that best applies to what you're looking for).

Going back to basics, my first Micscape paper is thus devoted to an early student microscope stand of the second mid of the 19th century. Thanks to its open design, this microscope is ideal for demonstrations, and also for oblique epi-darkfield illumination to reveal physical colors from diatoms.

http://www.microscopy-uk.org.uk/mag/imgmar10/JW_wat3.JPG

http://www.microscopy-uk.org.uk/mag/imgmar10/JW_wat10.jpg

JMC12 : nanophotonics nano-symposium

19 Mars 2010 , Rédigé par JW Publié dans #Nanophotonics pick

During the next national conference on condensed matter, I will be co-organizer of a "mini-colloque" devoted to nano-optics.

See the conference webpage, and the mini-colloque n°8.

Over 10,000 visits !

15 Février 2010 , Rédigé par JW Publié dans #Fancy lab

During its three-years existence, this blog has received over 10,000 visits, more than 26,000 pages have been viewed. I'm not sure that anybody got an answer to his/her questions; at least, people reading this blog will get some idea about what I spend my time on... Thanks for passing by !

Latest (review) paper : nanophotonics and FCS

10 Février 2010 , Rédigé par JW Publié dans #Recent research work

Published in the January issue of Int. J. Mol. Sci., this review is freely available for download here (4.1Mb).

Abstract: Recent advances in nanophotonics open the way for promising applications towards efficient single molecule fluorescence analysis. In this review, we discuss how photonic methods bring innovative solutions for two essential questions: how to detect a single molecule in a highly concentrated solution, and how to enhance the faint optical signal emitted per molecule? The focus is set primarily on the widely used technique of fluorescence correlation spectroscopy (FCS), yet the discussion can be extended to other single molecule detection methods.

http://www.mdpi.com/1422-0067/11/1/206/ag